2012/02/11

3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.


J Biol Chem. 2012 Jan 2;287(1):245-56. Epub 2011 Nov 7.

3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.

Source

Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.



Fig 2C b-actin blot has seams (enhance contrast and you will see it)






Fig. 2G/H - IKKa blot in panel G is IKKb blot from panel H flipped horizontally. IKKb blot in panel G is IKKa blot from panel H flipped horizontally.





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