Nimbolide sensitizes human colon cancer cells to TRAIL throughreactive oxygen species- and ERK-dependent up-regulation ofdeath receptors, p53, and Bax.

J Biol Chem. 2011 Jan 14;286(2):1134-46. Epub 2010 Nov 15.

Nimbolide sensitizes human colon cancer cells to TRAIL throughreactive oxygen species- and ERK-dependent up-regulation ofdeath receptorsp53, and Bax.


Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas M.D. AndersonCancer Center, Houston, Texas 77030, USA.

Fig. 3

Fig. 4B - seams above and below the band in DR4 blot.

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