A novel pentamethoxyflavone down-regulates tumor cellsurvival and proliferative and angiogenic gene products throughinhibition of IκB kinase activation and sensitizes tumor cells toapoptosis by cytokines and chemotherapeutic agents.

Mol Pharmacol. 2011 Feb;79(2):279-89. Epub 2010 Oct 7.

novel pentamethoxyflavone down-regulates tumor cellsurvival and proliferative and angiogenic gene products throughinhibition of IκB kinase activation and sensitizes tumor cells toapoptosis by cytokines and chemotherapeutic agents.

Phromnoi KReuter SSung BPrasad SKannappan RYadav VRChanmahasathien WLimtrakul P,Aggarwal BB.
Department of Experimental Therapeutics, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Box 143, Houston, TX 77030, USA.


Fig. 1B right panel, first 2 lanes of NFKB gel are cloned.


Fig. 2C lower panel, seam between lanes 2 and 3.


Fig. 3B

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