Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.

Cancer Res. 2008 Nov 1;68(21):8861-70.

Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.


Department of Experimental Therapeutics, Cytokine Research Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

Blood. 2009 Feb 26;113(9):2003-13. Epub 2008 Oct 24.

Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumolleads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis inleukemia cells.


Cytokine Research Laboratory, Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, TX 77030, USA

Figure 4D - p65C38S +/- Picroliv. Right 2 lanes are cloned.

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